On April 17 and May 22, 2026, Japan designated 117 PFHxS-related substances, long-chain perfluoroalkanoic acids (LC-PFCAs) and their salts, medium-chain chlorinated paraffins (MCCPs), and chlorpyrifos as Class I Specified Chemical Substances (Class I SCS)—the most stringent regulatory category under the Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc., also known as the Chemical Substances Control Act (CSCA). What are Class I SCS? Class I

Japan continues to strengthen its chemical management framework under the Chemical Substances Control Act (CSCA), introducing significant new restrictions on per- and polyfluoroalkyl substances (PFAS) and Persistent Organic Pollutants (POPs) in 2026. The latest amendments expand the scope of substances designated as Class I Specified Chemical Substances (Class I SCS)—the most stringent regulatory category under the CSCA—resulting in broad prohibitions on the manufacture, impo